After installing the latest version of Gnome 3 if you were shocked by the lack of usability and wondered how hard or impossible it was to configure small things, say, window font size then I have to confess that this is exactly what I also felt when I installed a fresh copy of Gnome 3 flavored Fedora.
Still, I'm a fan of Gnome 3 and after relevant customization I find it more usable than Windows 7 or OS X 10.8.
Here's a list of important changes I make. You may have to change the values of parameters so that they work well on your hardware.
1. Install custom fonts:
mkdir ~/.local/share/fonts
Dump your favorite fonts in this folder. My favorite are Verdana and Arial.
2. Improve the interface:
gsettings set org.gnome.desktop.interface text-scaling-factor '1.7'
gsettings set org.gnome.desktop.wm.preferences titlebar-font 'Arial Narrow Bold 0'
gsettings set org.gnome.desktop.interface font-name 'Arial Narrow 11'
gsettings set org.gnome.desktop.wm.keybindings close "['<Alt>Q']"
You might have noticed that now I have no way of closing a window with mouse. Only way to do is to press Alt-Q.
3. In mouse and touchpad settings enable "two finger scroll" and "tap to click"
4. Resize Gnome panel
http://useful-linux-tips.blogspot.in/2013/02/resize-gnome-panel.html
5. Remove unwanted entries from Nautilus
http://useful-linux-tips.blogspot.in/2013/02/modify-places-menu-in-nautilus-file.html
6. Remove all favorite apps from gnome panel except firefox, nautilus and one or two other apps that you frequently use.
7. I generally clear my home folder and tell browsers to directly download in my home folder from where I transfer important data (if any) to a different partition which is fully organized.
rmdir Public/ Documents/ Music/ Pictures/ Videos/ Templates/ Desktop/ Downloads/
8. Disable recent documents:
rm .local/share/recently-used.xbel; mkdir .local/share/recently-used.xbel
9. Remove all default bookmarks by erasing all contents of
vi .config/gtk-3.0/bookmarks
Rather, manually bookmark folders that you frequently visit.
10. Disable auto update from all accounts by command
gpk-prefs
11. Make fonts smooth if needed:
http://useful-linux-tips.blogspot.in/2013/01/smooth-font-rendering-on-fedora-18.html
That should make it usable enough.